Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for Graves' disease in three European Caucasian cohorts.

The thyroid stimulating hormone receptor (TSHR) gene is an established susceptibility locus for Graves' disease (GD), with recent studies refining association to two single nucleotide polymorphisms (SNPs), rs179247 and rs12101255, within TSHR intron 1.We aimed to validate association of rs17924...

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Main Authors: Rafał Płoski, Oliver J Brand, Beata Jurecka-Lubieniecka, Maria Franaszczyk, Dorota Kula, Paweł Krajewski, Muhammad A Karamat, Matthew J Simmonds, Jayne A Franklyn, Stephen C L Gough, Barbara Jarząb, Tomasz Bednarczuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2991361?pdf=render