Decreased expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T cells and peripheral blood from tuberculosis patients.

The vast majority of Mycobacterium tuberculosis (M. tuberculosis) infected individuals are protected from developing tuberculosis and T cells are centrally involved in this process. MicroRNAs (miRNA) regulate T-cell functions and are biomarker candidates of disease susceptibility and treatment effic...

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Main Authors: Katja Kleinsteuber, Kerrin Heesch, Stefanie Schattling, Malte Kohns, Claudia Sander-Jülch, Gerhard Walzl, Anneke Hesseling, Ertan Mayatepek, Bernhard Fleischer, Florian M Marx, Marc Jacobsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23613882/?tool=EBI