MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma

MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma

Summary: In pediatric neuroblastoma, MYCN-amplification correlates to poor clinical outcome and new treatment options are needed for these patients. Identifying the metabolic adaptations crucial for tumor progression may be a promising strategy to discover novel therapeutic targets. Here, we have co...

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Bibliographic Details
Main Authors: Ganna Oliynyk, María Victoria Ruiz-Pérez, Lourdes Sainero-Alcolado, Johanna Dzieran, Hanna Zirath, Héctor Gallart-Ayala, Craig E. Wheelock, Henrik J. Johansson, Roland Nilsson, Janne Lehtiö, Marie Arsenian-Henriksson
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219303992

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http://www.sciencedirect.com/science/article/pii/S2589004219303992

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