Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

Abstract Background Hispanic/Latino (HL) populations bear a disproportionately high burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk scores (PRS) offers great promise for improved screening and prevention. However, there are a number of complications rela...

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Bibliographic Details
Main Authors: Aroon T. Chande, Lavanya Rishishwar, Andrew B. Conley, Augusto Valderrama-Aguirre, Miguel A. Medina-Rivas, I. King Jordan
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Medical Genetics
Subjects:
Polygenic risk score (PRS)
Genetic risk
Type 2 diabetes (T2D)
Genetic ancestry
Population genetics
Hispanic/Latino (HL)
Online Access:http://link.springer.com/article/10.1186/s12881-020-01068-0

Internet

http://link.springer.com/article/10.1186/s12881-020-01068-0

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