Molecular and Structural Basis of Cross-Reactivity in <i>M. tuberculosis</i> Toxin–Antitoxin Systems

Molecular and Structural Basis of Cross-Reactivity in <i>M. tuberculosis</i> Toxin–Antitoxin Systems

<i>Mycobacterium tuberculosis</i> genome encodes over 80 toxin–antitoxin (TA) systems. While each toxin interacts with its cognate antitoxin, the abundance of TA systems presents an opportunity for potential non-cognate interactions. TA systems mediate manifold interactions to manage pat...

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Bibliographic Details
Main Authors: Himani Tandon, Akhila Melarkode Vattekatte, Narayanaswamy Srinivasan, Sankaran Sandhya
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Toxins
Subjects:
toxin–antitoxin
<i>M. tuberculosis</i>
bacteria
pathogenesis
protein–protein interactions
cross-talk
Online Access:https://www.mdpi.com/2072-6651/12/8/481

Internet

https://www.mdpi.com/2072-6651/12/8/481

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