H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets.

A pandemic-capable influenza virus requires a hemagglutinin (HA) surface glycoprotein that is immunologically unseen by most people and is capable of supporting replication and transmission in humans. HA stabilization has been linked to 2009 pH1N1 pandemic potential in humans and H5N1 airborne trans...

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Bibliographic Details
Main Authors: Marion Russier, Guohua Yang, Atanaska Marinova-Petkova, Peter Vogel, Bryan S Kaplan, Richard J Webby, Charles J Russell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5362248?pdf=render