Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock.

Genome-wide association study (GWAS) loci for several immunity-mediated diseases (early onset asthma, inflammatory bowel disease (IBD), primary biliary cholangitis, and rheumatoid arthritis) map to chromosomal region 17q12-q21. The predominant view is that association between 17q12-q21 alleles and i...

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Bibliographic Details
Main Authors: Matthew L Chang, Sanny Moussette, Enrique Gamero-Estevez, José Héctor Gálvez, Victoria Chiwara, Indra R Gupta, Aimee K Ryan, Anna K Naumova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223212