Design of a 3D BMP-2-Delivering Tannylated PCL Scaffold and Its Anti-Oxidant, Anti-Inflammatory, and Osteogenic Effects In Vitro

Design of a 3D BMP-2-Delivering Tannylated PCL Scaffold and Its Anti-Oxidant, Anti-Inflammatory, and Osteogenic Effects In Vitro

In this study, a novel three-dimensional (3D) bone morphogenic protein-2 (BMP-2)-delivering tannylated polycaprolactone (PCL) (BMP-2/tannic acid (TA)/PCL) scaffold with anti-oxidant, anti-inflammatory, and osteogenic activities was fabricated via simple surface coating with TA, followed by the immob...

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Bibliographic Details
Main Authors: Jae Yong Lee, Hyunwoong Lim, Jae Won Ahn, Dongsik Jang, Seung Hee Lee, Kyeongsoon Park, Sung Eun Kim
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
bone morphogenic protein-2 (BMP-2)
tannic acid (TA)
polycaprolactone (PCL)
3D scaffold
anti-oxidation
anti-inflammation
osteogenic differentiation
Online Access:https://www.mdpi.com/1422-0067/19/11/3602

Internet

https://www.mdpi.com/1422-0067/19/11/3602

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