MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

Abstract Background By regulating target genes, microRNAs play essential roles in carcinogenesis and drug resistance in human pancreatic ductal adenocarcinoma (PDAC). Previous studies have shown that microRNA-10a-5p (miR-10a-5p) is overexpressed in PDAC and acts as an oncogene to promote the metasta...

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Bibliographic Details
Main Authors: Guangbing Xiong, Hua Huang, Mengyu Feng, Gang Yang, Suli Zheng, Lei You, Lianfang Zheng, Ya Hu, Taiping Zhang, Yupei Zhao
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-10a-5p
TFAP2C
PDAC
Chemoresistance
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13046-018-0739-x

Internet

http://link.springer.com/article/10.1186/s13046-018-0739-x

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