Dense genotyping of immune-related loci identifies variants associated with clearance of HPV among HIV-positive women in the HIV epidemiology research study (HERS).

Persistent high-risk human papillomavirus (HR-HPV) is a necessary and causal factor of cervical cancer. Most women naturally clear HPV infections; however, the biological mechanisms related to HPV pathogenesis have not been clearly elucidated. Host genetic factors that specifically regulate immune r...

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Bibliographic Details
Main Authors: Staci L Sudenga, Howard W Wiener, Caroline C King, Anne M Rompalo, Susan Cu-Uvin, Robert S Klein, Keerti V Shah, Jack D Sobel, Denise J Jamieson, Sadeep Shrestha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053382?pdf=render