Therapeutic value of voltage-gated sodium channel inhibitors in breast, colorectal and prostate cancer: a systematic review

Therapeutic value of voltage-gated sodium channel inhibitors in breast, colorectal and prostate cancer: a systematic review

Although survival rates of breast, colon and prostate cancers are improving, deaths from these tumors frequently occur due to metastasis. Voltage-gated Na+ channels (VGSCs) are membrane proteins, which regulate membrane current and cellular migration during nervous system organogenesis. VGSCs are al...

Full description

Bibliographic Details
Main Authors: Fabiola eMartin, Chiedu eUfodiama, Ian eWatt, Martin eBland, William J Brackenbury
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
Anticonvulsants
Breast Neoplasms
Carbamazepine
Colonic Neoplasms
Phenytoin
Prostatic Neoplasms
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00273/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00273/full

Similar Items