The Role of Thiamine Pyrophosphate in Prevention of Cisplatin Ototoxicity in an Animal Model

Objective. The aim of this study was to evaluate the effectiveness of thiamine pyrophosphate against cisplatin-induced ototoxicity in guinea pigs. Materials and Methods. Healthy guinea pigs (n=18) were randomly divided into three groups. Group 1 (n=6) received an intraperitoneal injection of saline...

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Bibliographic Details
Main Authors: Ozan Kuduban, Cuneyt Kucur, Ebru Sener, Halis Suleyman, Fatih Akcay
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/182694