Flexibility of short ds-DNA intercalated by a dipyridophenazine ligand

Flexibility of short ds-DNA intercalated by a dipyridophenazine ligand

We use Förster Resonant Energy Transfer (FRET) in order to measure the increase of flexibility of short ds-DNA induced by the intercalation of dipyridophenazine (dppz) ligand in between DNA base pairs. By using a DNA double strand fluorescently labeled at its extremeties, it is shown that the end-to...

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Bibliographic Details
Main Authors: Fuchao eJia, Stéphane eDespax, Jean-Pierre eMunch, Pascal eHébraud
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Chemistry
Subjects:
Ruthenium Compounds
FRET
DNA intercalation
DNA flexibility
dppz intercalator
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00025/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00025/full

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