Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome

Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome

Alcohol use disorders are common both in the United States and globally, and are associated with a variety of co-morbid, inflammation-linked diseases. The pathogenesis of many of these ailments are driven by the activation of the NLRP3 inflammasome, a multi-protein intracellular pattern recognition...

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Bibliographic Details
Main Authors: Laura R. Hoyt, Matthew J. Randall, Jennifer L. Ather, Daniel P. DePuccio, Christopher C. Landry, Xi Qian, Yvonne M. Janssen-Heininger, Albert van der Vliet, Anne E. Dixon, Eyal Amiel, Matthew E. Poynter
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717300733

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http://www.sciencedirect.com/science/article/pii/S2213231717300733

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