Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle
Abstract Background Single-step genomic best linear unbiased prediction (SSGBLUP) is a comprehensive method for genomic prediction. Point estimates of marker effects from SSGBLUP are often used for genome-wide association studies (GWAS) without a formal framework of hypothesis testing. Our objective...
Main Authors: | , , , , , |
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Format: | Article |
Language: | deu |
Published: |
BMC
2019-06-01
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Series: | Genetics Selection Evolution |
Online Access: | http://link.springer.com/article/10.1186/s12711-019-0469-3 |