Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

Abstract Background Single-step genomic best linear unbiased prediction (SSGBLUP) is a comprehensive method for genomic prediction. Point estimates of marker effects from SSGBLUP are often used for genome-wide association studies (GWAS) without a formal framework of hypothesis testing. Our objective...

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Bibliographic Details
Main Authors: Ignacio Aguilar, Andres Legarra, Fernando Cardoso, Yutaka Masuda, Daniela Lourenco, Ignacy Misztal
Format: Article
Language:deu
Published: BMC 2019-06-01
Series:Genetics Selection Evolution
Online Access:http://link.springer.com/article/10.1186/s12711-019-0469-3

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http://link.springer.com/article/10.1186/s12711-019-0469-3

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