Olefin-accelerated solid-state C–N cross-coupling reactions using mechanochemistry

Cross-coupling reactions have been achieved in solution, yet tend to be inefficient in a solid state. Here, the authors report a solid-state palladium-catalyzed Buchwald-Hartwig cross-coupling using olefins as molecular dispersants, enabling reduction of solvent waste.

Bibliographic Details
Main Authors: Koji Kubota, Tamae Seo, Katsumasa Koide, Yasuchika Hasegawa, Hajime Ito
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08017-9