PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis

Aims: Poly (ADP-ribose) polymerase (PARP) inhibitor has been reported to attenuate inflammatory response in rat models of inflammation. This study was designed to investigate the effect of PARP signalling in osteoarthritis (OA) cartilage inflammatory response in an OA rat model. Methods: The OA mode...

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Bibliographic Details
Main Authors: Zili Liu, Honglin Wang, Shaoqian Wang, Jie Gao, Lei Niu
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-07-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.107.BJR-2020-0200.R2