Enhancement of dendritic persistent Na+ currents by mGluR5 leads to an advancement of spike timing with an increase in temporal precision

Abstract Timing and temporal precision of action potential generation are thought to be important for encoding of information in the brain. The ability of single neurons to transform their input into output action potential is primarily determined by intrinsic excitability. Particularly, plastic cha...

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Bibliographic Details
Main Authors: Weonjin Yu, Jong-Woo Sohn, Jaehan Kwon, Suk-Ho Lee, Sooyun Kim, Won-Kyung Ho
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-018-0410-7