Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

Abstract Background Mobile elements are a major source of structural variants in the human genome, and some mobile elements can regulate gene expression and transcript splicing. However, the impact of polymorphic mobile element insertions (pMEIs) on gene expression and splicing in diverse human tiss...

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Bibliographic Details
Main Authors: Xiaolong Cao, Yeting Zhang, Lindsay M. Payer, Hannah Lords, Jared P. Steranka, Kathleen H. Burns, Jinchuan Xing
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Genome Biology
Subjects:
Quantitative trait loci
Gene expression regulation
Alternative splicing
Transposable elements
Polymorphic mobile element insertions
Online Access:http://link.springer.com/article/10.1186/s13059-020-02101-4

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http://link.springer.com/article/10.1186/s13059-020-02101-4

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