Resolution of bleomycin-induced murine pulmonary fibrosis via a splenic lymphocyte subpopulation

Resolution of bleomycin-induced murine pulmonary fibrosis via a splenic lymphocyte subpopulation

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease with high mortality, and the pathogenesis of the disease is still incompletely understood. Although lymphocytes, especially CD4+CD25+FoxP3+ regulatory T cells (Tregs), have been implicated in the development of IPF, con...

Full description

Bibliographic Details
Main Authors: Koichiro Kamio, Arata Azuma, Kuniko Matsuda, Jiro Usuki, Minoru Inomata, Akemi Morinaga, Takeru Kashiwada, Nobuhiko Nishijima, Shioto Itakura, Nariaki Kokuho, Kenichiro Atsumi, Hiroki Hayashi, Tomoyoshi Yamaguchi, Kazue Fujita, Yoshinobu Saito, Shinji Abe, Kaoru Kubota, Akihiko Gemma
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Respiratory Research
Subjects:
Regulatory T cells
Idiopathic pulmonary fibrosis
Fibroblast growth factor 9
Interleukin-10
Chemokine (CC motif) ligand-2
Splenectomy
Online Access:http://link.springer.com/article/10.1186/s12931-018-0783-2

Internet

http://link.springer.com/article/10.1186/s12931-018-0783-2

Similar Items