Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro.

Galectin-1 (gal-1) is a carbohydrate-binding lectin with important functions in angiogenesis, immune response, hemostasis and inflammation. Comparable functions are exerted by platelet factor 4 (CXCL4), a chemokine stored in the α-granules of platelets. Previously, gal-1 was found to activate platel...

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Bibliographic Details
Main Authors: Annemiek Dickhout, Bibian M E Tullemans, Johan W M Heemskerk, Victor L J L Thijssen, Marijke J E Kuijpers, Rory R Koenen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244736