Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.

African Americans have been understudied in genome wide association studies of diabetes and related traits. In the current study, we examined the joint association of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) with fasting insulin and an index of insulin resistance (HOMA-...

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Main Authors: Marguerite R Irvin, Nathan E Wineinger, Treva K Rice, Nicholas M Pajewski, Edmond K Kabagambe, Charles C Gu, Jim Pankow, Kari E North, Jemma B Wilk, Barry I Freedman, Nora Franceschini, Uli Broeckel, Hemant K Tiwari, Donna K Arnett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3162025?pdf=render