An Efficient Synthesis of Novel Pyrazole-Based Heterocycles as Potential Antitumor Agents

A new series of pyrazolylpyridines was prepared by reaction of ethyl-3-acetyl-1,5-diphenyl-1H-pyrazole-4-carboxylate with the appropriate aldehyde, malononitrile, or ethyl acetoacetate and an excess of ammonium acetate under reflux in acetic acid. Similarly, two novel bipyridine derivatives were pre...

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Bibliographic Details
Main Authors: Magda A. Abdallah, Sobhi M. Gomha, Ikhlass M. Abbas, Mariam S. H. Kazem, Seham S. Alterary, Yahia N. Mabkhot
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/7/8/785