Enhanced solubility and antimicrobial activity of alamethicin in aqueous solution by complexation with γ-cyclodextrin

Alamethicin (ALM) inhibits the growth of bacteria by disrupting their cell membrane. ALM exhibits poor solubility in aqueous medium thus limiting its application. A method is proposed for encapsulation of ALM with γ-cyclodextrin (γ-CD) by forming a complex of higher solubility with thermal and pH st...

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Bibliographic Details
Main Authors: Meng-Ke Zhang, Yuan Lyu, Xiao Zhu, Jin-Peng Wang, Zheng-Yu Jin, Ganesan Narsimhan
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617307442