The nonstructural proteins of Pneumoviruses are remarkably distinct in substrate diversity and specificity

Abstract Background Interferon (IFN) inhibits viruses by inducing several hundred cellular genes, aptly named ‘interferon (IFN)-stimulated genes’ (ISGs). The only two RNA viruses of the Pneumovirus genus of the Paramyxoviridae family, namely Respiratory Syncytial Virus (RSV) and Pneumonia Virus of M...

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Bibliographic Details
Main Authors: Michael Ribaudo, Sailen Barik
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Virology Journal
Subjects:
ISG
Online Access:http://link.springer.com/article/10.1186/s12985-017-0881-7