Particle-size dependent effects in the Balb/c murine model of inhalational melioidosis

Deposition of Burkholderia pseudomallei within either the lungs or nasal passages of the Balb/c murine model resulted in different infection kinetics. The infection resulting from the inhalation of B. pseudomallei within a 12 um particle aerosol was prolonged compared to a 1 um particle aerosol with...

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Bibliographic Details
Main Authors: Richard eThomas, Carwyn eDavies, Alejandro eNunez, Stephen eHibbs, Lin eEastaugh, Sarah eHarding, Janine eJordan, Kay eBarnes, Petra eOyston, Steve eEley
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00101/full