A drug-sensitive genetic network masks fungi from the immune system.

Fungal pathogens can be recognized by the immune system via their beta-glucan, a potent proinflammatory molecule that is present at high levels but is predominantly buried beneath a mannoprotein coat and invisible to the host. To investigate the nature and significance of "masking" this mo...

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Bibliographic Details
Main Authors: Robert T Wheeler, Gerald R Fink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1447670?pdf=render