Direct inhibitory effects of pioglitazone on hepatic fetuin-A expression.

Fetuin-A, a circulating glycoprotein synthesized in the liver, is involved in insulin resistance and type 2 diabetes. However, regulation of fetuin-A synthesis has remained obscure. We previously reported that pioglitazone treatment significantly reduced serum fetuin-A levels in patients with type 2...

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Main Authors: Akinobu Ochi, Katsuhito Mori, Masanori Emoto, Shinya Nakatani, Tomoaki Morioka, Koka Motoyama, Shinya Fukumoto, Yasuo Imanishi, Hidenori Koyama, Eiji Ishimura, Masaaki Inaba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923806?pdf=render