Regeneration of stereocilia of hair cells by forced Atoh1 expression in the adult mammalian cochlea.

The hallmark of mechanosensory hair cells is the stereocilia, where mechanical stimuli are converted into electrical signals. These delicate stereocilia are susceptible to acoustic trauma and ototoxic drugs. While hair cells in lower vertebrates and the mammalian vestibular system can spontaneously...

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Bibliographic Details
Main Authors: Shi-Ming Yang, Wei Chen, Wei-Wei Guo, Shuping Jia, Jian-He Sun, Hui-Zhan Liu, Wie-Yen Young, David Z Z He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3459923?pdf=render