MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease

MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease

Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by a loss of dopaminergic neurons (DN) in the substantia nigra (SN). Several lines of evidence suggest that apoptotic cell death of DN is driven in part by non-cell autonomous mechanisms implicating microglial c...

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Bibliographic Details
Main Authors: Kiyoka Kinugawa, Yann Monnet, Lixia Lu, Amaury J. Bekaert, Clotilde Théry, Ziad Mallat, Etienne C. Hirsch, Stéphane Hunot
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Neurobiology of Disease
Subjects:
Lactadherin
MFGE8
Dopaminergic neurons
Phagocytosis
Neurodegenerative disease
MPTP
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112003737

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http://www.sciencedirect.com/science/article/pii/S0969996112003737

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