Inhibition of the PI3K-Akt-mTOR signaling pathway in T lymphocytes in patients with active tuberculosis

Inhibition of the PI3K-Akt-mTOR signaling pathway in T lymphocytes in patients with active tuberculosis

Objectives: To investigate PI3K-Akt-mTOR signaling pathway changes and the proliferation of FoxP3+Treg cells in patients with active tuberculosis. Methods: We isolated PBMCs and CD4+CD25+FoxP3+Treg cells from peripheral blood collected from patients with active tuberculosis and healthy controls. We...

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Bibliographic Details
Main Authors: XueXuan Zhang, TengYi Huang, Ying Wu, WenGuang Peng, HanBin Xie, MeiChen Pan, HuanBin Zhou, BoZhi Cai, YingE Wu
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:International Journal of Infectious Diseases
Subjects:
PI3K-Akt-mTOR pathway
T lymphocytes
FoxP3+Treg cells
Mycobacterium tuberculosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217301157

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http://www.sciencedirect.com/science/article/pii/S1201971217301157

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