Variability in Estrogen-Metabolizing Genes and Their Association with Genomic Instability in Untreated Breast Cancer Patients and Healthy Women

In the present study, we investigated the relationship between polymorphisms in the estrogen-metabolizing genes CYP17, CYP1B1, CYP1A1, and COMT and genomic instability in the peripheral blood lymphocytes of 62 BC patients and 62 controls considering that increased or prolonged exposure to estrogen c...

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Bibliographic Details
Main Authors: Raquel Alves dos Santos, Ana Cláudia Teixeira, Mônica Beatriz Mayorano, Hélio Humberto Angotti Carrara, Jurandyr Moreira de Andrade, Catarina Satie Takahashi
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2011/571784