DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.

DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.

<h4>Background</h4>The natural triterpenes, erythrodiol and uvaol, exert anti-inflammatory, vasorelaxing and anti-proliferative effects. Angiotensin II is a well-known profibrotic and proliferative agent that participates in the cardiac remodeling associated with different pathological s...

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Bibliographic Details
Main Authors: Ruben Martín, Maria Miana, Raquel Jurado-López, Ernesto Martínez-Martínez, Nieves Gómez-Hurtado, Carmen Delgado, Maria Visitación Bartolomé, José Alberto San Román, Claudia Cordova, Vicente Lahera, Maria Luisa Nieto, Victoria Cachofeiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22844495/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22844495/?tool=EBI

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