Development and effects of tacrolimus-loaded nanoparticles on the inhibition of corneal allograft rejection

Tacrolimus has been widely applied to prevent organ rejection after transplantation. However, the conventional pharmaceutical formulation of tacrolimus limits its applications in ocular therapy due to its hydrophobicity and low corneal penetrability. We optimized tacrolimus-loaded methoxy poly (ethy...

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Bibliographic Details
Main Authors: Qianni Wu, Dong Liu, Xulin Zhang, Dongni Wang, Meimei DongYe, Wan Chen, Duoru Lin, Fangming Zhu, Weirong Chen, Haotian Lin
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2019.1582728