Extensive White Matter Alterations and Its Correlations with Ataxia Severity in SCA 2 Patients.

Previous studies of SCA2 have revealed significant degeneration of white matter tracts in cerebellar and cerebral regions. The motor deficit in these patients may be attributable to the degradation of projection fibers associated with the underlying neurodegenerative process. However, this relations...

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Bibliographic Details
Main Authors: Carlos R Hernandez-Castillo, Victor Galvez, Roberto Mercadillo, Rosalinda Diaz, Aurelio Campos-Romo, Juan Fernandez-Ruiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4532454?pdf=render