Optimized Treatment Schedules for Chronic Myeloid Leukemia.

Over the past decade, several targeted therapies (e.g. imatinib, dasatinib, nilotinib) have been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to therapy, drug resistance remains a problem for some CML patients. Recent studies have shown that resistance mutations tha...

Full description

Bibliographic Details
Main Authors: Qie He, Junfeng Zhu, David Dingli, Jasmine Foo, Kevin Zox Leder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5072565?pdf=render