Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.

Class II MHC molecules display peptides on the cell surface for the surveillance by CD4+ T cells. To ensure that these ligands accurately reflect the content of the intracellular MHC loading compartment, a complex processing pathway has evolved that delivers only stable peptide/MHC complexes to the...

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Bibliographic Details
Main Authors: Shashank Gupta, Sabine Höpner, Bernd Rupp, Sebastian Günther, Katharina Dickhaut, Noopur Agarwal, M Cristina Cardoso, Ronald Kühne, Karl-Heinz Wiesmüller, Günther Jung, Kirsten Falk, Olaf Rötzschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2265549?pdf=render

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http://europepmc.org/articles/PMC2265549?pdf=render

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