Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis.

Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis.

In recent decades, the incidence of candidemia in tertiary hospitals worldwide has substantially increased. These infections are a major cause of morbidity and mortality; in addition, they prolong hospital stays and raise the costs associated with treatment. Studies have reported a significant incre...

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Bibliographic Details
Main Authors: João B A Neto, Cecília R da Silva, Maria A S Neta, Rosana S Campos, Janaína T Siebra, Rose A C Silva, Danielle M Gaspar, Hemerson I F Magalhães, Manoel O de Moraes, Marina D P Lobo, Thalles B Grangeiro, Tatiane S C Carvalho, Emilay B T Diogo, Eufrânio N da Silva Júnior, Felipe A R Rodrigues, Bruno C Cavalcanti, Hélio V N Júnior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4015898?pdf=render

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http://europepmc.org/articles/PMC4015898?pdf=render

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