A boolean model of the cardiac gene regulatory network determining first and second heart field identity.

Two types of distinct cardiac progenitor cell populations can be identified during early heart development: the first heart field (FHF) and second heart field (SHF) lineage that later form the mature heart. They can be characterized by differential expression of transcription and signaling factors....

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Bibliographic Details
Main Authors: Franziska Herrmann, Alexander Groß, Dao Zhou, Hans A Kestler, Michael Kühl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462786?pdf=render