Thymoquinone Selectively Induces Hepatocellular Carcinoma Cell Apoptosis in Synergism With Clinical Therapeutics and Dependence of p53 Status

Thymoquinone (TQ) is a natural compound extracted from the black seeds of Nigella sativa Linn. belonging to the Ranunculaceae family. TQ exhibits anti-inflammatory and antineoplastic activities against various cancers. Many therapeutics in hepatocellular carcinoma (HCC) treatments, such as doxorubic...

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Bibliographic Details
Main Authors: Shah Jehan, Chen Zhong, Guangyue Li, Syed Zulqarnain Bakhtiar, Dangdang Li, Guangchao Sui
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
p53
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.555283/full