Cell Sheets from Adipose Tissue MSC Induce Healing of Pressure Ulcer and Prevent Fibrosis via Trigger Effects on Granulation Tissue Growth and Vascularization
We report a comparative study of multipotent mesenchymal stromal cells (MSC) delivered by injection, MSC-based cell sheets (CS) or MSC secretome to induce healing of cutaneous pressure ulcer in C57Bl/6 mice. We found that transplantation of CS from adipose-derived MSC resulted in reduction of fibros...
Main Authors: | Natalya Alexandrushkina, Peter Nimiritsky, Roman Eremichev, Vladimir Popov, Mikhail Arbatskiy, Natalia Danilova, Pavel Malkov, Zhanna Akopyan, Vsevolod Tkachuk, Pavel Makarevich |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/15/5567 |
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