The Glucocorticoid Receptor NR3C1 in Testicular Peritubular Cells is Developmentally Regulated and Linked to the Smooth Muscle-Like Cellular Phenotype

The Glucocorticoid Receptor NR3C1 in Testicular Peritubular Cells is Developmentally Regulated and Linked to the Smooth Muscle-Like Cellular Phenotype

Whether glucocorticoids (GC) can directly affect human testicular functions is not well understood. A predominant site of GC receptor (GR; <i>NR3C1</i>) expression in the adult testis are peritubular smooth muscle-like cells, which express smooth muscle actin (ACTA2), contract and thereb...

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Bibliographic Details
Main Authors: Harald Welter, Carola Herrmann, Nils Dellweg, Annika Missel, Christiane Thanisch, Henryk F. Urbanski, Frank-Michael Köhn, J. Ullrich Schwarzer, Annette Müller-Taubenberger, Artur Mayerhofer
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Journal of Clinical Medicine
Subjects:
human male fertility
human testis
dexamethasone
elastin
glucocorticoid
cytoskeleton
Online Access:https://www.mdpi.com/2077-0383/9/4/961

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https://www.mdpi.com/2077-0383/9/4/961

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