Dynamic network-based epistasis analysis: Boolean examples

Dynamic network-based epistasis analysis: Boolean examples

In this review we focus on how the hierarchical and single-path assumptions of epistasis analysis can bias the topologies of gene interactions infered. This has been acknowledged in several previous papers and reviews, but here we emphasize the critical importance of dynamic analyses, and specifical...

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Bibliographic Details
Main Authors: Eugenio eAzpeitia, Mariana eBenítez, Pablo ePadilla-Longoria, Carlos eEspinosa-Soto, Elena R. Alvarez-Buylla
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Plant Science
Subjects:
Gene Regulatory Networks
modeling
Epistasis
temporal dynamics
Boolean networks
feedback loops
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2011.00092/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2011.00092/full

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