Towards Mutation-Specific Precision Medicine in Atypical Clinical Phenotypes of Inherited Arrhythmia Syndromes

Towards Mutation-Specific Precision Medicine in Atypical Clinical Phenotypes of Inherited Arrhythmia Syndromes

Most causal genes for inherited arrhythmia syndromes (IASs) encode cardiac ion channel-related proteins. Genotype-phenotype studies and functional analyses of mutant genes, using heterologous expression systems and animal models, have revealed the pathophysiology of IASs and enabled, in part, the es...

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Bibliographic Details
Main Authors: Tadashi Nakajima, Shuntaro Tamura, Masahiko Kurabayashi, Yoshiaki Kaneko
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
atrial fibrillation
atypical clinical phenotype
Brugada syndrome
early repolarization syndrome
long QT syndrome
mutation
Online Access:https://www.mdpi.com/1422-0067/22/8/3930

Internet

https://www.mdpi.com/1422-0067/22/8/3930

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