Enhanced myelopoiesis and aggravated arthritis in S100a8-deficient mice.

Enhanced myelopoiesis and aggravated arthritis in S100a8-deficient mice.

Expressed strongly by myeloid cells, damage-associated molecular pattern (DAMP) proteins S100A8 and S100A9 are found in the serum of patients with infectious and autoimmune diseases. Compared to S100A9, the role of S100A8 is controversial. We investigated its biological activity in collagen-induced...

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Main Authors: Annabelle Cesaro, Joan Defrêne, Asmaa Lachhab, Nathalie Pagé, Mélanie R Tardif, Amin Al-Shami, Tamas Oravecz, Paul R Fortin, Jean-François Daudelin, Nathalie Labrecque, Fawzi Aoudjit, Martin Pelletier, Philippe A Tessier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221528

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https://doi.org/10.1371/journal.pone.0221528

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