Urine Donor–Derived Cell-Free DNA Helps Discriminate BK Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients With BK Polyomavirus Infection

Urine Donor–Derived Cell-Free DNA Helps Discriminate BK Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients With BK Polyomavirus Infection

Background: Studies have shown that plasma donor–derived cell-free DNA (dd-cfDNA) can predict renal allograft antibody-mediated rejection. This study was performed to evaluate the value of urine dd-cfDNA concentration and dd-cfDNA fraction (%) for discriminating BK polyomavirus-associated nephropath...

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Bibliographic Details
Main Authors: Xu-Tao Chen, Wen-Fang Chen, Jun Li, Rong-Hai Deng, Yang Huang, Shi-Cong Yang, Pei-Song Chen, Ting-Ya Jiang, Hai-Tao Liu, Chang-Xi Wang, Li-Zhong Chen, Jiang Qiu, Gang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
BK polyomavirus
BK polyomavirus-associated nephropathy
donor-derived cell-free DNA
area under the curve
prediction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01763/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01763/full

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