Development and validation of a salivary tau biomarker in Alzheimer's disease

Abstract Introduction Total tau (t‐tau) and phosphorylated tau (p‐tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau is also present in the salivary gland tissue and saliva, and salivary measures might produce an accurate, accessi...

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Bibliographic Details
Main Authors: Heather Pekeles, Hamid Y. Qureshi, Hemant K. Paudel, Hyman M. Schipper, Mervyn Gornistky, Howard Chertkow
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
FTD
Online Access:https://doi.org/10.1016/j.dadm.2018.03.003