Function of mouse embryonic stem cell-derived supporting cells in neural progenitor cell maturation and long term expansion.

BACKGROUND: In the differentiation of mouse embryonic stem (ES) cells into neurons using the 5-stage method, cells in stage 4 are in general used as neural progenitors (NPs) because of their ability to give rise to neurons. The choice of stage 4 raises several questions about neural progenitors such...

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Bibliographic Details
Main Authors: Yunqian Guan, Qing-An Du, Wanwan Zhu, Chunlin Zou, Di Wu, Ling Chen, Yu Alex Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544757?pdf=render