Immunological discrimination between the human apolipoprotein E2(Arg158—-Cys) and E3 isoforms.

A specific anti-apoE2(Arg158—-Cys) monoclonal antibody was raised by means of immunization of mice with a variant specific synthetic peptide. The peptide sequences used were homologous to apolipoprotein E of human and mouse. Consequently, the mouse immune system was tolerant to most of the selected...

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Bibliographic Details
Main Authors: K Gerritse, P de Knijff, G van Ierssel, LM Havekes, RR Frants, MM Schellekens, N D Zegers, E Claassen, WJ Boersma
Format: Article
Language:English
Published: Elsevier 1992-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520415470